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NOTE: The usual dose for GLUCOPHAGE
is 1 - 2 pills daily, for type 2 diabetes |
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MISSED DOSAGE
| INTERACTIONS
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USES
The following Information is intended to supplement,
not substitute for, the expertise and judgment of your
physician, pharmacist or other healthcare professional.
It should not be construed to indicate that use of the
drug is safe, appropriate, or effective for you.
Consult your healthcare professional before
using any of our products.
Metformin (met-FOR-min) is used to treat a type of diabetes
mellitus (sugar diabetes) called type 2 diabetes. With
this type of diabetes, insulin produced by the pancreas
is not able to get sugar into the cells of the body
where it can work properly. Using metformin alone, with
a type of oral antidiabetic medicine called a sulfonylurea,
or with insulin will help to lower blood sugar when
it is too high and help restore the way you use food
to make energy.
Many people can control type 2 diabetes with diet alone
or diet and exercise. Following a specially planned
diet and exercising will always be important when you
have diabetes, even when you are taking medicines. To
work properly, the amount of metformin you take must
be balanced against the amount and type of food you
eat and the amount of exercise you do. If you change
your diet, your exercise, or both, you will want to
test your blood sugar to find out if it is too low.
Your health care professional will teach you what to
do if this happens.
At some point, this medicine may stop working as well
and your blood glucose will increase. You will need
to know if this happens and what to do. Instead of taking
more of this medicine, your doctor may want you to change
to another antidiabetic medicine. If that does not lower
your blood sugar, your doctor may have you stop taking
the medicine and begin receiving insulin injections
instead.
Metformin does not help patients who have insulin-dependent
or type 1 diabetes because they cannot produce insulin
from their pancreas gland. Their blood glucose is best
controlled by insulin injections.
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HOW TO TAKE THIS MEDICATION
Glucophage comes in tablets to take by mouth. It
usually is taken two or three times a day with meals.
Follow the directions on your prescription label carefully,
and ask your doctor or pharmacist to explain any part
you do not understand. Take Glucophage exactly as directed.
Do not take more or less of it or take it more often
than prescribed by your doctor. Metformin hydrochloride
extended-release tablets should be swallowed whole.
Do not break, chew, or crush. Continue to take Metformin
hydrochloride even if you feel well. Do not stop taking
Metformin hydrochloride without talking to your doctor.
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SIDE EFFECTS
Although side effects from Metformin hydrochloride
are not common, they can occur. If you have any of these
symptoms, eat or drink a food or beverage with sugar
in it, such as hard candy or fruit juice, and call your
doctor immediately; symptoms of low blood sugar (hypoglycemia)
include:
- shakiness
- dizziness
- rapid heartbeat
- sweating or confusion
- blurred vision
- headache
- numbness or tingling of the mouth
- weakness
- fatigue
- pale color - sudden hunger
If
you have any of these symptoms, call your doctor immediately;
symptoms of high blood sugar (hyperglycemia) i-nclude:
- thirst
- dry mouth
- tiredness
- flushing
- dry skin
- frequent urination
- loss of appetite
- trouble breathing
If you experience any of the following symptoms,
or those listed in the IMPORTANT WARNING section,
call your doctor immediately:
- seizures
- loss of consciousness
- skin rash
- itching or redness
- exaggerated sunburn
- yellowing of the skin or eyes
- light-colored stools
- dark urine
- unusual bleeding or bruising
- fever
- sore throat
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PRECAUTIONS
Before taking Glucophage,
- tell your doctor and pharmacist if you are allergic
to Glucophage or any other drugs.
- tell your doctor and pharmacist what prescription
and nonprescription medications you are taking, especially
cimetidine (Tagamet), diuretics ('water pills'), nifedipine
(Procardia), and vitamins. in addition to the conditions
listed in the IMPORTANT WARNING section, tell your
doctor if you have or have ever had heart, pituitary,
or thyroid disease; adrenal insufficiency; a severe
infection; or hormone problems.
- tell your doctor if you are pregnant, plan to become
pregnant, or are breast-feeding. If you become pregnant
while taking Metformin hydrochloride, call your doctor.
- if you are having surgery, including dental surgery,
tell the doctor or dentist that you are taking Glucophage.
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DRUG INTERACTION
Although certain medicines should not be used together
at all, in other cases two different medicines may be
used together even if an interaction might occur. In
these cases, your doctor may want to change the dose,
or other precautions may be necessary. Do not take any
other medicine unless prescribed or approved by your
doctor . When you are taking metformin, it is especially
important that your health care professional know if
you are taking any of the following:
- AlcoholSmall amounts of alcohol taken with meals do
not usually cause a problem; however, either larger
amounts of alcohol taken for a long time or a large
amount of alcohol taken in one sitting without food
can increase the effect of metformin. This can keep
the blood sugar low for a longer period of time than
normal
- Amiloride (e.g., Midamor) or
- Calcium channel blocking agents (amlodipine [e.g.,
Norvasc], bepridil [e.g., Bepadin], diltiazem [e.g.,
Cardizem], felodipine [e.g., Plendil], flunarizine [e.g.,
Sibelium], isradipine [e.g., DynaCirc], nicardipine
[e.g., Cardene], nifedipine [e.g., Procardia], nimodipine
[e.g., Nimotop], verapamil [e.g., Calan]) or * Cimetidine
(e.g., Tagamet) or
- Digoxin (heart medicine) or
- Furosemide (e.g., Lasix) or
- Morphine (e.g., M S Contin) or
- Procainamide (e.g., Pronestyl) or
- Quinidine (e.g., Quinidex) or
- Quinine (malaria medicine) or
- Ranitidine (e.g., Zantac) or
- Triamterene (e.g., Dyrenium) or
- Trimethoprim (e.g., Proloprim) or
- Vancomycin (e.g., Vancocin)Use with metformin may
cause high blood levels of metformin, which may increase
the chance of low blood sugar or side effects
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MISSED DOSAGE
If you miss a dose, take it as soon as you can.
If it is almost time for your next dose, take only that
dose. Do not take double or extra doses.
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STORAGE
Store at room temperature between 59 and 86 degrees
F (15-30 degrees C) away from light and moisture. Keep
this and all medications out of the reach of children.
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